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If
you suffer from chronic hives, you may be taking one or more medications to
treat the itch. Itchy red welts are the defining hallmark of most cases of this
skin condition, also known as chronic urticaria. Chronic hives, as opposed to
acute hives, last six weeks or longer. And although it’s typically fairly
simple to identify the triggers of acute hives, chronic hives are a bit tougher
to figure out. Experts don’t yet know the underlying cause of chronic hives,
but studies are showing links between chronic conditions and environmental
factors. Here’s what we know so far.

  • 1.

    Stress

    Researchers
    suggest stress may play a role in chronic urticaria. They aren’t ready to
    proclaim that stress definitely triggers your case of chronic hives, but if
    your stress level is through the roof, it could exacerbate your hives–or
    possibly make them last longer.

    portrait of stressed woman

  • 2.

    Temperature

    Changes
    in temperature trigger the welts to develop in some people who have a version
    of chronic hives called physical urticaria. Some are more susceptible to the
    cold, while heat is more of a trigger for others. And when your own temperature
    goes up, your sweat might even trigger the hives to develop.

    Young Asian American man wiping sweat off forehead with towel under direct sunshine

  • 3.

    Physical Contact

    Rubbing,
    scratching, pressure, and constriction can all trigger hives in people with
    physical urticaria. Sun exposure can also trigger hives.

    woman itching her arm

  • 4.

    Thyroid Disease

    Autoimmune
    thyroid disease has been linked to some cases of chronic hives. Scientists are
    still researching the possible mechanism, and there are lots of theories under
    review. But if you have chronic hives with no other known cause, it might be
    worth asking your allergist or dermatologist about getting tested for thyroid
    disease. It’s possible you could have the elevated antithyroid antibodies associated
    with certain thyroid disorders like Hashimoto’s disease.

    Doctor examining man's neck

  • 5.

    Liver Disease

    Hepatitis
    B, which is a type of liver disease, has been associated with chronic
    urticaria. However, many people with hepatitis C also develop an acute form of
    hives, so researchers are looking at the possibility of a relationship between
    cases of hepatitis C and chronic hives, too.

    doctor examining patient's stomach

  • 6.

    Cancer

    It’s
    definitely rare, but a few cases of cancer have been linked to chronic hives.
    And at least one large population-based study suggests  people with chronic hives may be at increased
    risk for developing certain kinds of cancer, like cancer of the blood or lymph
    nodes. However, experts caution that more research is needed.

    cancer patient sitting by window in head wrap

  • 7.

    Celiac Disease

    Because
    it’s not annoying enough to have to cope with abdominal pain, bloating,
    diarrhea, and the other typical symptoms of celiac disease, you may also have
    to cope with an itchy red rash. Chronic hives are already associated with some
    other autoimmune conditions, and celiac disease is considered an
    “immune-mediated disease.”

    young woman sitting on couching with stomach pain

  • 8.

    Lupus

    As
    we’ve already noted, some autoimmune diseases have been linked to some cases of
    chronic hives. Add lupus to the list. Again, it’s not common, but some people
    develop autoimmune urticaria as an early symptom of lupus.

    black woman in thought

  • 9.

    Unknown Causes

    This
    is the catch-all category, but for good reason. Far and away, most cases of
    chronic hives can’t be traced back to a specific cause. Chronic hives that
    don’t have a known cause are called chronic idiopathic urticaria. Idiopathic
    literally means “cause unknown.” As many as 80% of cases of chronic hives fit
    into this category. But researchers are working hard to determine the root of
    chronic hives, and today we have more treatment options than ever before,
    thanks to this work.

    gettyimages 168360236

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Medical Reviewers: William C. Lloyd III

Last Review Date: 2019 Feb 19

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